1. Introduction

Ms. Kankana Das:
Ph.D (Submitted)
kankana.das@tmckolkata.com

 

2. Research experience

From under-graduation to PhD thesis submission, I completed my educational qualifications from the Department of Physiology, University of Calcutta. Thus, my educational and training attributes are primarily in the domain of Human Physiology and allied sciences. In my research career spanning 8 years, I have successfully managed diverse research projects to achieve specific research goals. I have worked for more than 6 years towards my PhD thesis in Physiology that entailed developing a DAG-rich formulation involving potent lipases to counter manifestations of potentially chronic pre-clinical conditions of induced-toxicity. I have an extensive experience in handling clinical samples and developing oil-based nutraceuticals against myriad pre-clinical disease models. I wish to leverage on my past research credentials and make avenues in the domain of research activities that has more palpable translational impact, particularly in the domain of cancer manifestations including leukemia and gall-bladder cancer. Over 8 years in the domain of basic research in countering toxicity, hypertension, and other life-style diseases in pre-clinical models. 6 months at TTCRC.

3. Research interest

Identifying molecular and therapeutic targets in the manifestations of Leukaemia and Gall Bladder cancer. Play an active role (as a resource person) in developing the biobank repository cancer explants at the TTCRC for further scientific investigations.  

4. Current Project

Research assistant and Bio-banker,involved in the multifarious research activities at TTCRC in the domain of childhood acute lymphoblastic leukaemia (ALL) and Gall-bladder cancer.

5. Previous working experience

 Worked as a Senior Research Fellow (April 2015-March 2019) in a project entitled “Studies on Antioxidative and Anti–platelet aggregative Properties of DAG rich Rice Bran Oil and DAG rich Mustard Oil” (Sanctioned by Department of Health Research and ICMR, letter no. GIA/53/2014-DHR dated 05.01.2015) under the supervision of Dr. Mahua Ghosh, Associate Professor, Department Of Chemical Technology (Oil Laboratory), University of Calcutta.

Also worked as a Research Fellow (January 22nd,2013-March, 2015) in athe project entitled ‘Studies on characterization of content and composition of the aromatic oil and microstructures of the speed spices grown in different districts of West Bengal’ sanctioned by Dept. of Science & Technology, Govt. of West Bengal, vide sanction letter No. 416 (Sanc.)/ST/P/S&T/2G-5/2011; dated September 09, 2011, under the supervision of Dr. MahuaGhosh, Assiociate Professor, Department Of Chemical Technology (Oil Laboratory), University of Calcutta.

6. Publication

  1.  Das, K., Kundu, A., Karmakar, S. and Ghosh, M., 2020. Novel structured diacylglycerol (DAG) rich oleo formulations activate the Nrf2 pathway and impedes NF-κB translocation to mitigate pre-clinical conditions of hypertension. Journal of Functional Foods, 64, p.103650.
  2. Das, K. and Ghosh, M., 2019. Comparative qualitative assessment of DAG production from medium chain fatty acids mediated by enzymatic and chemical catalysts under individually optimized conditions. Biocatalysis and Agricultural Biotechnology, 22, p.101422.
  3. Das K and Ghosh M. Structured DAG oil ameliorates renal injury in streptozotocin- induced diabetic rats through inhibition of NF-B and activation of Nrf2 pathway. Food and Chemical Toxicology. 100 (2017) 225-238.
  4. Dhar T M, Das K and Ghosh M. Studies on surface morphology of aromatic oil containing black cumin seeds. Journal of Science and Culture.Vol 81. 2015 ;( 11-12).
  5. Das K, Dhar T M and Ghosh M. A comparative study of the antioxidative properties of the different seed spices available in India.Journal of Advanced Pharmacy Education & Research.Vol 5. Jan-Mar 2015, Issue 1.
  6. Das DK, Sinha M, Khan A, Das K, Manna K, Dey S. Radiation protection by major tea polyphenol, Epicatechin. International Journal of Human Genetics. 2013 Mar 1;13(1):59- 64.