(Associate Prof. of Paediatric Haematology)
The main focus of my research is to study prenatal B lymphopoiesis in order to understand the origins of childhood leukaemia, in particular infant acute lymphoblastic leukaemia (ALL). Prenatal B lymphopoiesis is different from adult B cell development; and developmentally-regulated characteristics of fetal B-progenitors are likely to provide the ‘oncogenic’ cellular context necessary to co-operate with MLL rearrangements to induce infant ALL.
The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Our work spans from early proof-of-concept fundamental science all the way up to its application in clinical settings.