2. Research & Interest
After completing my M.Sc in 2004, I’ve started my research career as a PhD student at Chittaranjan National Cancer Institute and was working on trans-membrane intergrin receptor and its role in cancer progression. During this, I had learned cellular biology and molecular biology techniques to study integrin-mediated outside-in and inside-out signaling cascades. With this basic understanding in receptor biology and tumour metastasis, I completed my PhD work on investigating the effect of All-Trans Retinoic Acid (ATRA) on integrin receptors, its interaction with the extracellular matrix and alteration in expression and activation of matrix metalloproteinases in 2010.
After completion of my PhD, I have received Young Scientist award from Dept of Science and Technology. I wanted to further extend my research interest on tumour matrix interaction and moved to USA with a Postdoctoral Fellowship at Thomas Jefferson University. I worked on investigating the role of integrin and growth factor receptor cross-talk and their downstream signaling cascade with respect to disease progression in prostate cancer.
After completing my first postdoctoral fellowship at Jefferson, I desire to focus on translational research which could benefit patients with cancer. I have joined Tata Translational Cancer Research in 2014. After my joining at TTCRC, I got the opportunity to gain training on high-throughput proteomics and microscopy. I moved to University of Manchester and gained experience on different mass spectrometry-based discovery and targeted proteomics approaches. I also have learnt the applications of automated high-throughput confocal microscopy. Further to continue I want to apply my knowledge and expertise to understand tumour-stroma interaction within its microenvironment in respect to disease progression. Currently, my research focus on understanding the aetiopathology of gallbladder cancer in India.